Wednesday, July 22, 2009

Alessio Fasano Article in Scientific American

Dr. Alessio Fasano's substantial article "Celiac Disease Insights: Clues to Solving Autoimmunity" is in the August 2009 Scentific American.

Have at it!

19 comments:

ELLEN said...

I miss you David!

Tiffany said...

David will greatly be missed. I just can't believe this sad news. My thoughts go out to his family. We would all like to say "thanks" to David for making our gluten-free visits to NYC truly wonderful!

ben cappel said...

David - you were a friend. I always had the greatest respect for you. I will miss our debates and randomly bumping into each other at Peter's. I still can't believe you're gone -- all of a sudden. My hopes and prayers go out to your family and your parents...I know you were doing everything to try to take care of them. Rest in peace.

ByTheBay said...

I am so so sad to hear about the loss of David, the wonderful blogger at Gluten-Free NYC. He will be missed even by those of us who never met him!

TCB said...

Very sad to hear the news as well. David was extremely informative, a must-read for me. May he rest in peace/

loretta said...

David helped me so much when I first diagnosed. He will truly be missed. May he rest in peace. My thoughts and prayers go out to his family,

Jeff said...

David was really cool!

Sonia Gluten Free said...

Hello friend,

I wish you a pregnta, as is the maximum allowed of gluten in products in NY? 20ppm think, but I'm not sure, Could you confirm please.
thank you very much
sonia gluten free

ben cappel said...

Hi Sonia - just to let you know, David, author of Gluten Free NYC passed away recently. There will be a memorial dinner on Sept 14 in NYC. To answer your question, yes, the U.S. FDA is using 20ppm as their upper limit to allow a GF label...although this isn't enforced for restaurants, only packaged foods sold commercially.

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Clayburn Griffin said...

Have you ever been to GustOrganics? It has a lot of gluten-free options, plus it's 100% organic. You should post about it sometime.

Nicole said...

David, I'm a reporter doing a story about a gluten-free Thanksgiving. I'm on a tight deadline -- any chance you can talk today? My email is nbode@dnainfo.com and my cell is 646-265-5489. Thanks!

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cymbri said...

Celiac disease is an autoimmune disease due to high gluten antibodies
Oral Tolerance is the one of the Great discoveries of Modern Medicine because it lowers production of Antibodies .

 Proof: Autoimmune Inc. - a company established from the Success in Animal trials using Oral Tolerance for various immune diseases – arthritis, diabetes, experimental MS and other illnesses. there was success in animal trials, but it was all premature because there was NO human trial success for these same diseases. The company dissolved because it missed some important details that brought success on their animal test. This company was just one step to reaching success but could go no further and does not exist today.

For more info on Oral Tolerance, please view:
http://suite101.com/article/oral-tolerance-therapy-a8796

To achieve success, it is important to examine the few Successful O.T. Trials on humans:

Below are links 4 Examples of O.T. Success
1.) Successful treatment of oral-tolerance in netherton syndrome
http://www.elsevier.es/en/revistas/allergologia-et-immunopathologia-105/successful-induction-of-oral-tolerance-in-netherton-90154860-research-letters-2012
2.) Successful oral tolerance induction in severe peanut allergy http://onlinelibrary.wiley.com/doi/10.1111/j.1398-9995.2009.01982.x/abstract

3.) Oral Desensitization in Children With Cow’s Milk Allergy
http://www.jiaci.org/issues/vol18issue5/11.pdf

4.) 92.5% Success Oral tolerance to egg protein
http://www.sciencesway.com/vb/showthread.php?t=80825#.UOOw-Kyy_Gg

The cases above are successful because subjects were children. In animal trials, research used 4 month old mice and 6 month old rats – the common denominator in animal tests and children's success is All subjects were young – their immune systems produce a lymphokine (factor produced by lymphocytes) and we include this together with Oral
Tolerance to achieve success in Human Treatments.


The mechanism of O.T. is made possible by the T Suppressor cell that lowers antibodies – in O.T., this cell lowers 3 antibodies -Immunoglobin M, Immunoglobin G and immunoglobin E & this is good news because Immunoglobins G & M are involved in most cases of Autoimmune diseases.

The T cell needs 2 factors or signals for full activation:
1.) a peptide similar to gluten- we can not use gluten since it causes celiac, we get a peptide instead - this primes or makes ready the T cell. But without the 2nd signal the T cell remains in anergy( no activity).                                                                           
2.) the Second signal - is CD80 or CD86 - either one is enough to make the T cell go thru the changes that makes it a fully activated cell.
This info is found at: http://en.wikipedia.org/wiki/Co-stimulation


In most humans with autoimmune disease, there is Second signal -CD80/86 but not enough to heal.


However, there are other ways which produce that necessary 2nd signal and NO DANGER.
 
The second signal is a blood factor &  can be induced by HERBS.
Two herbs that induce Second Signal -CD80 & CD86 production are: 1.) Agaricus bisporus - is the white Button mushroom or champignon mushroom found in most U.S. and Canadian supermarkets.
See article http://www.ncbi.nlm.nih.gov/pubmed/18287364                     
2.) Goji berry known as Lycium barbarum - juice and extracts induces CD80- available from most Food supplement stores & the internet. See article http://www.ncbi.nlm.nih.gov/pubmed/19170138

Modern Medicine & Research do not use herbs in their Trials and Experiments and that's the reason they have not succeeded.

This treatment is simple - it contains a peptide (part of protein) which is the Oral Tolerance part and herbs -that's all.

A course is 26 days
For mild cases – need 3 to 5 courses treatments, Moderate cases - 6 to 8 courses, Severe cases - 9 to 11 courses.

Questions or inquiries?
Contact us via kimberlite36@yahoo.ca